Article
SGLT-2 inhibitors May Decrease Recurrent Gout Flares in Patients with Type 2 diabetes
May 1, 2024
Dr. Bernal Clinical question: Do SGLT-2 inhibitors decrease gout flares in patients with type 2 diabetes and a known history of gout? Background: Sodium–glucose cotransporter-2 inhibitors...
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Rituximab likely raises risk of hospital death in COVID-19 patients
December 2, 2021
In a retrospective study of hospitalized COVID-19 patients, “only 1 of 303 drugs examined, rituximab, was associated with an increased risk of in-hospital death ... both when used for rheumatologic as well as for cancer therapy.”
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‘Misleading’ results in colchicine COVID-19 trials meta-analysis
November 23, 2021
“While the small studies are potentially insight providing, the large studies are the only ones worth giving our attention to in the context of the meta-analysis.”
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Two swings, two misses with colchicine, Vascepa in COVID-19
September 1, 2021
The study cohorts varied from healthcare and public workers at high risk for infection to individuals already hospitalized with COVID-19.
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Tocilizumab shortage continues as pandemic wears on
August 19, 2021
Emergency use authorization of tocilizumab for COVID-19 has led to a global shortage, but supplies for rheumatoid arthritis and other inflammatory conditions are faring better – for now.
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Patients with rheumatic disease may experience flares after SARS-CoV-2 vaccination
June 28, 2021
A total of 202 SRD flares were reported by 165 patients (14.9%).
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Mavrilimumab may aid severe COVID-19 recovery
June 10, 2021
The granulocyte/macrophage-colony stimulating factor (GM-CSF) blocker reduced the need for mechanical ventilation and death by day 29 versus placebo.
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Hypertension worsened by commonly used prescription meds
May 6, 2021
Close to 20% of U.S. adults with hypertension are on a prescription drug, such as NSAIDs, known to raise blood pressure, creating an opportunity for drug substitution.
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Psoriasis associated with an increased risk of COVID-19 in real-world study
April 28, 2021
Those treated with TNF-alpha inhibitors, methotrexate, and apremilast had statistically lower risks of COVID-19 vs. those on topical therapy.
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Arthritis drug may curb myocardial damage in acute STEMI
April 13, 2021
Tocilizumab appears to improve myocardial salvage by helping tamp down the inflammatory overshoot that occurs during infarction and reperfusion.
