Article
Inhaled Amikacin in the First 72 Hours of Mechanical Ventilation Reduced the Incidence of VAP
January 1, 2025
Clinical question: Does inhaled amikacin reduce the incidence of ventilator-associated pneumonia (VAP) in critically ill patients? Background: VAP is a common and serious complication in patients on...
Article
Clinical Risk Score Predicts Arterial Thrombosis in Survivors of Intracranial Hemorrhage
January 1, 2025
Clinical question: Among survivors of hemorrhagic stroke, who is at high long-term risk of arterial thrombosis? Background: Patients who survive intracerebral hemorrhage (ICH) are at increased risk...
Article
Acute Cardiac Events are Common Among Adults 50 Years or Older Hospitalized with RSV and Associated with Severe Disease
December 2, 2024
Clinical question: How common are acute cardiac events among hospitalized older adults (50 years or older) with respiratory syncytial virus (RSV) infection and what are the associated risk...
Article
Gabapentinoids and Risk for Severe Exacerbation in COPD
December 2, 2024
Clinical question: Is gabapentinoid use associated with severe exacerbation in patients with chronic obstructive pulmonary disease (COPD)? Background: The U.S. Food and Drug Administration issued a...
Article
Coding Corner: Spoonful of Sugar
October 1, 2024
A 46-year-old woman is admitted to the hospital with an exacerbation of chronic obstructive pulmonary disease (COPD) requiring intensification of her inhaler regimen, initiation of corticosteroids,...
Article
Comparing Outcomes of Targeted Reperfusion Therapy Versus Anticoagulation in Patients with Acute Intermediate-high-risk PE
October 1, 2024
Ms. Jang Clinical question: Do patients with acute intermediate-high-risk pulmonary embolism (PE) benefit more in terms of cardiac function from reperfusion therapy with conventional...
Article
DAPT Versus Alteplase for Patients With Minor Non-disabling Acute Ischemic Stroke
April 1, 2024
Clinical question: Is dual antiplatelet therapy (DAPT) non-inferior to intravenous thrombolysis in patients with minor non-disabling acute ischemic stroke? Background: Intravenous thrombolytics are...
Article
DOACs Versus LMWH and Recurrent VTE in Patients with Cancer
March 1, 2024
Clinical question: Are direct oral anticoagulants (DOACs) acceptable compared to low-molecular-weight heparin (LMWH) for preventing venous thromboembolism (VTE) with a safe bleeding risk in cancer...
Article
Aspirin Thromboprophylaxis is Non-inferior to LMWH for Prevention of Death and Pulmonary Embolism after Orthopedic Trauma
March 1, 2024
Clinical question: Is aspirin as effective as low-molecular-weight heparin (LMWH) for thromboprophylaxis in patients with orthopedic trauma? Background: Studies have outlined the benefits of...
Article
Demystifying Performance Measures for Hospitalists: VTE Prophylaxis
March 1, 2024
As venous thromboembolism (VTE) became an increasingly recognized cause of death in hospitalized patients, prevention became a high priority for the health care system.1,2 Starting in 2005, the Joint...