Article
Cellulitis is Frequently Misdiagnosed
December 1, 2023
Clinical question: How accurate is the initial diagnosis of cellulitis in adult patients compared to subsequent specialist consultation? Dr. Lessing Background: Diagnosis of cellulitis leads...
PE Presents in 1/3 of Patients with Recent Onset of Exertional Dyspnea
December 1, 2023
Clinical question: What is the prevalence of pulmonary embolism (PE) among emergency department (ED) patients with recent onset (less than one month) of exertional dyspnea? Dr....
Article
Anticoagulation for AFib Increases Bleeding Risk and Death in Patients Over 65 with Cognitive Impairment
December 1, 2023
Clinical question: In older patients with atrial fibrillation (AFib), does frailty or cognitive function affect the risk of anticoagulation use? Dr. Enix Background: In older patients with...
Article
Administering Glucocorticoids Lowers Risk of Death in ICU Patients with Severe CAP
December 1, 2023
Clinical question: Does early administration of glucocorticoids to intensive care unit (ICU) patients with severe community-acquired pneumonia (CAP) reduce mortality? Ms. Harakal Background:...
Article
Gaps Remain in Hospital Discharge Education
December 1, 2023
Clinical question: What are medicine floor patients told about their hospital discharge instructions and by whom? Dr. Mutter Background studies: Prior studies have demonstrated suboptimal...
Article
Systemic Corticosteroids for Patients with Severe CAP
December 1, 2023
Clinical question: Among patients hospitalized with community-acquired pneumonia (CAP), does the addition of corticosteroids reduce mortality? Dr. Salline Background: Corticosteroids are used...
Article
Transcatheter Arterialization Provides Safe and Effective Treatment for No-option CLI
December 1, 2023
Clinical question: Is transcatheter arterialization of lower extremity deep veins safe and effective in preventing above-ankle amputation in patients with advanced chronic limb ischemia (CLI) who are...
Article
Direct Oral Challenge is Non-inferior to Skin Testing in Low-risk Penicillin Allergy Patients
October 2, 2023
Clinical question: Is there an alternative to penicillin skin testing for low-risk penicillin allergies? Dr. Miller Background: While approximately 10% of the population report...
Article
Deprescribing Medications Among Older Adults from the End of Hospitalization Through Post-acute Care
October 2, 2023
Clinical question: Can inpatient deprescribing interventions upon post-acute care facility discharge reduce the total medication burden? Dr. Kaur Background: Polypharmacy remains a common...
Article
Weighing Benefits and Risks of Indefinite Anticoagulation in First Unprovoked VTE
October 2, 2023
Clinical question: Is indefinite anticoagulation beneficial for patients with a first unprovoked venous thromboembolism (VTE) after initial treatment? Dr. Sheikh Background: VTE is a chronic,...