Article
Frequent PT in Hospital Increases Home Discharge for Pneumonia Patients
June 3, 2024
Clinical question: Does increased frequency of physical therapy (PT) for hospitalized pneumonia patients affect their discharge to home versus to a post-acute care facility? Background: Each year,...
Article
Elevated fibrinogen and D-dimer relative to C-reactive protein linked to cognitive deficits post-COVID-19 hospitalization
June 3, 2024
Clinical question: Are acute blood biomarker profiles predictive of cognitive deficits following COVID-19 hospitalizations? Background: Cognitive deficits have been observed in many patients after...
Article
Liberal transfusion strategy in acute myocardial infarction patients with anemia not shown to significantly reduce recurrent MI or death
June 3, 2024
Clinical question: What should be the transfusion target for patients hospitalized for myocardial infarction (MI) with anemia? Background: Data on the optimal transfusion target for patients with MI...
Article
High-sensitivity versus conventional troponin in assessing PE risk
June 3, 2024
Clinical question: Is high-sensitivity cardiac troponin I (hs-cTnI) better at predicting outcomes for hemodynamically stable pulmonary embolism (PE) than conventional cardiac troponin I...
Article
Limited utility in using NT-proBNP rather than functional capacity to estimate risk of perioperative MACE
June 3, 2024
Clinical question: Does adding N-terminal pro–B-type natriuretic peptide (NT-proBNP) to clinical risk scores provide a better estimate of the risk of major adverse cardiac events (MACE) among...
Article
Semaglutide reduces major adverse cardiovascular events by 20% in patients with cardiovascular disease
June 3, 2024
Clinical question: Does semaglutide reduce cardiovascular events in non-diabetics with cardiovascular disease? Background: While glucagon-like peptide-1 (GLP-1) agonists reduce cardiovascular events...
Article
Comparing in-hospital adverse events in elderly postoperative delirium patients: haloperidol versus atypical antipsychotics
June 3, 2024
Clinical question: Are in-hospital adverse events worse in post-operative delirium patients treated with haloperidol compared to atypical antipsychotics? Background: Post-operative delirium is...
Article
Hydrocortisone reduces mortality in severe CAP
June 3, 2024
Clinical question: Does early hydrocortisone therapy reduce mortality among patients with severe community-acquired pneumonia (CAP) requiring admission to an intensive care unit (ICU) or intermediate...
Article
Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF
May 1, 2024
Dr. Watson Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)? Background: Studies have shown an increased risk of...
Article
High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF
May 1, 2024
Dr. Watson Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery,...