Article
Transthoracic Echocardiography is Superior in Detecting Valvular Heart Disease
September 1, 2022
Ms. Nowak Clinical question: To quantify the extent to which undetectable heart sounds occur in hospitalized patients who are undergoing transthoracic echocardiography and evaluate the...
Article
Acute Care for the Elderly in the Home Environment Increased Physical Activity Levels While Lowering Costs, Health Care Use, and Readmissions
September 1, 2022
Dr. Nagaraj Clinical question: Can hospital-level care be provided in the home environment to reduce costs without compromising the quality of care in the U.S.? Background: Inpatient care is...
Article
Mirtazapine is Not an Effective Treatment for Agitation in Dementia
September 1, 2022
Ms. Whalen CLINICAL QUESTION: What’s the clinical effectiveness and safety profile of mirtazapine in reducing agitation in dementia relative to placebo? BACKGROUND: Nonpharmacological...
Article
Oral Antibiotics and a Combination Regimen of IV and Oral Antibiotics for Treatment of Acute Uncomplicated Appendicitis Yielded Similar Success Rates
September 1, 2022
Dr. Andleeb Clinical question: Are oral antibiotics effective and non-inferior to a combination of intravenous and oral antibiotics? Background: Evidence over the past 10 years suggests that...
Article
Low-dose Rivaroxaban at Discharge Prevented Some VTE Events at One Month for High-risk Patients Recovering from COVID-19
September 1, 2022
Dr. Thazhatuveetil-Kunhahamed Clinical Question: Is extended rivaroxaban prophylaxis (10 mg daily for 35 days) protective against arterial and venous thromboembolism (VTE) events in COVID-19...
Article
The risk for intestinal necrosis with SPS is very low
August 1, 2022
Dr. Lippert Clinical question: What is the risk of intestinal necrosis with sodium polystyrene (SPS) for the treatment of hyperkalemia? Background: SPS is a medication that has been available...
Article
Initiation of pulmonary rehabilitation after admission for COPD exacerbation decreases rehospitalizations
August 1, 2022
Ms. Langford Clinical question: Does the initiation of pulmonary rehabilitation after hospitalization for a chronic obstructive pulmonary disease (COPD) exacerbation impact...
Article
Tranexamic acid minimized perioperative bleeding in patients undergoing noncardiac surgery
August 1, 2022
Dr. Menon Clinical question: Does tranexamic acid reduce the incidence of life-threatening perioperative bleeding in patients undergoing noncardiac surgery without increasing the risk of major...
Article
IV fluid resuscitation at a slow rate in ICU patients did not reduce 90-day mortality
August 1, 2022
Mr. Haller Clinical question: Is there a difference in the 90-day mortality for patients admitted to the ICU receiving a fast (999 mL/hour) versus slow (333 mL/hour) IV infusion...
Article
DES reduce the risk of ISR in patients with ICAS compared to BMS
August 1, 2022
Dr. Snipe Clinical question: In patients with symptomatic high-grade intracranial atherosclerotic stenosis (ICAS), does the use of a drug-eluting stent (DES) reduce the incidence of in-stent...