Article
Using Naltrexone for AUD is Safe in Patients With and Without Liver Disease
June 1, 2023
Dr. Hoang Clinical question: Is naltrexone hepatically safe for the treatment of alcohol use disorder (AUD) in patients with and without liver disease? Background: Treatment of underlying AUD...
Article
Moderate Fluid Resuscitation Preferred Over Aggressive Resuscitation in Acute Pancreatitis
June 1, 2023
Dr. Houston Clinical question: Does early, aggressive, fluid resuscitation improve clinical outcomes in acute pancreatitis when compared to moderate fluid resuscitation? Background: Studies...
Article
Daily Low-dose Aspirin Associated With Increased Serious Fall Risk in Healthy Older Adults
June 1, 2023
Dr. Le Clinical question: Does daily low-dose aspirin for primary prevention decrease fractures and fall-related hospital presentations in healthy older adults? Background: Falls and resulting...
Article
Apixaban Has Lower Risk of Bleeding Than Warfarin in ESKD
June 1, 2023
Dr. Leiner Clinical question: In patients with end-stage kidney disease (ESKD) and venous thromboembolism (VTE), does apixaban have a lower bleeding risk and VTE recurrence than...
Article
Lidocaine May Be More Beneficial Than Amiodarone for Management of In-hospital Cardiac Arrest
June 1, 2023
Clinical question: Are amiodarone and lidocaine associated with different outcomes for the treatment of in-hospital cardiac arrests? Background: Both amiodarone and lidocaine are recommended in the...
Article
Procalcitonin to Predict Severity of Acute Cholangitis and Need for Urgent Biliary Decompression
May 1, 2023
Dr. Ally Clinical question: What impact does procalcitonin have on the management of acute cholangitis? Background: Procalcitonin has been used to predict disease severity that may lead...
Article
The Association of Hallway Boarding on Readmission and Mortality Rates
May 1, 2023
Dr. Childers Clinical question: Does inpatient hallway boarding increase in-hospital mortality, 30-day mortality, or 30-day readmission rates? Background: Prior studies have reported that the...
Article
Implementation of a Comprehensive Hospitalist-led Initiative to Improve Care for Patients with OUD
May 1, 2023
Clinical question: Can a multidisciplinary, hospitalist-led program improve care for hospitalized patients with opioid use disorder (OUD)? Background: Despite rising opioid-related hospitalizations...
Article
Early Treatment with Thiamine and Mortality Among Patients with AUD Who are Hospitalized for Pneumonia
May 1, 2023
Dr. Chace Clinical question: Does early thiamine administration improve mortality outcomes for patients with alcohol use disorder who are hospitalized for pneumonia? Background: Wernicke’s...
Article
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis
May 1, 2023
Dr. Hammond Clinical question: Is early, aggressive, fluid resuscitation in acute pancreatitis or moderate fluid resuscitation the best and safest way to prevent progression to moderately severe...