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News
What are indications, complications of acute blood transfusions in sickle cell anemia? Key Points Additional Reading
March 17, 2017
Transfusion has many serious and life-threatening potential adverse effects; conduct thorough risk-benefit analysis for each individual sickle cell patient. Whenever possible, intensive phenotypically matched and leukoreduced RBCs should be used.
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News
Taking the hammer to sickle pain crises
February 1, 2017
Clinical question: Are any novel medicines designed to interrupt the pathophysiology of vaso-occlusion available to reduce the frequency and severity of pain crises in sickle cell anemia?
Article
Blood thinning with bioprosthetic valves
January 10, 2017
Blood thinning with bioprosthetic valvesClinical question: Does anticoagulation prevent thromboembolic events in patients undergoing bioprosthetic valve implantation?Background: The main advantage of bioprosthetic valves, compared with mechanical valves, is the avoidance of long-term anticoagula...
News
Increased death rate with platelets for aspirin/clopidogrel GI bleed
November 28, 2016
Patients with normal platelet counts who have a GI bleed while on antiplatelets were almost six times more likely to die in the hospital if they had a platelet transfusion, in a retrospective cohort study from the Yale University.
