Article
Therapeutic-Dose Anticoagulation Shortened the Duration of ACS in Sickle Cell Disease Without Increasing Major Bleeding Risk
September 3, 2025
Clinical question: Does therapeutic-dose anticoagulation, compared to prophylactic dosing, improve clinical outcomes in adults with sickle cell disease hospitalized for acute chest syndrome...
Article
Antibiotic Treatment for 7 days is Noninferior to 14 days in Patients with Uncomplicated Bacteremia
June 2, 2025
Clinical question: Is seven days of antibiotic treatment for bloodstream infections noninferior to 14 days of treatment? Background: Bloodstream infections are very common, can originate from a...
Article
Restrictive Transfusion in MI May Lead to an Increase in 6-Month Mortality
June 2, 2025
Clinical question: How does a restrictive transfusion strategy (transfusion threshold of 7 to 8 g/dL) compare to a liberal transfusion strategy (transfusion threshold of 10 g/dL) in patients with...
Article
Should Hospitalists Throw Caution to the Wind? Overly Cautious Correction of Severe Hyponatremia May Lead to Greater Harm Than Good
June 2, 2025
Clinical question: Does the correction rate for hospitalized adults with severe hyponatremia correlate with mortality or length of stay? Background: Hyponatremia is a commonly encountered problem...
Article
Gram-Negative Bacteremia: Early Transition from IV to PO Antibiotic Therapy
March 4, 2025
Clinical question: What is the safety and efficacy of switching from IV to oral antibiotic therapy after three to five days in patients with gram-negative bacteremia? Background: Bacteremia is...
Article
Slower Correction of Sodium in Severe Hyponatremia is Associated with Increased Mortality and Length of Stay
March 4, 2025
Clinical question: Is the sodium correction rate in severe hyponatremia associated with mortality and length of stay? Background: Hyponatremia is commonly encountered in the hospital, with high...
Article
Interpretation of Serum Ammonia Level
December 2, 2024
A 77-year-old woman with a history of hepatitis C cirrhosis presents to the emergency department with 24 hours of progressive confusion and disorientation. The physical exam is notable for...
Article
When Should I Transfuse My Adult Hospitalized Patient Who Has Anemia?
December 2, 2024
Update to the 2017 article When should I transfuse a patient who has anemia? Case An 82-year-old woman with chronic lymphocytic leukemia complicated by anemia of chronic disease (baseline...
Article
Challenging Anticoagulation Scenarios: How to Have Smooth Sailing through Choppy Waters
July 1, 2024
Keeping abreast of updates in anticoagulation guidelines is important for physicians to provide optimal patient care. Multiple changes to recommendations for anticoagulation have been made in the...
Article
Solving Major Problems: Major Bleeding and Major Surgery for Patients on Anticoagulants
July 1, 2024
This interactive session posed real-life scenarios for hospitalists who frequently deal with difficult anticoagulation questions and grounded it all with the evidence. The first case discussed was...