Article
Gram-Negative Bacteremia: Early Transition from IV to PO Antibiotic Therapy
March 4, 2025
Clinical question: What is the safety and efficacy of switching from IV to oral antibiotic therapy after three to five days in patients with gram-negative bacteremia? Background: Bacteremia is...
Article
Slower Correction of Sodium in Severe Hyponatremia is Associated with Increased Mortality and Length of Stay
March 4, 2025
Clinical question: Is the sodium correction rate in severe hyponatremia associated with mortality and length of stay? Background: Hyponatremia is commonly encountered in the hospital, with high...
Article
Interpretation of Serum Ammonia Level
December 2, 2024
A 77-year-old woman with a history of hepatitis C cirrhosis presents to the emergency department with 24 hours of progressive confusion and disorientation. The physical exam is notable for...
Article
When Should I Transfuse My Adult Hospitalized Patient Who Has Anemia?
December 2, 2024
Update to the 2017 article When should I transfuse a patient who has anemia? Case An 82-year-old woman with chronic lymphocytic leukemia complicated by anemia of chronic disease (baseline...
Article
Challenging Anticoagulation Scenarios: How to Have Smooth Sailing through Choppy Waters
July 1, 2024
Keeping abreast of updates in anticoagulation guidelines is important for physicians to provide optimal patient care. Multiple changes to recommendations for anticoagulation have been made in the...
Article
Solving Major Problems: Major Bleeding and Major Surgery for Patients on Anticoagulants
July 1, 2024
This interactive session posed real-life scenarios for hospitalists who frequently deal with difficult anticoagulation questions and grounded it all with the evidence. The first case discussed was...
Article
Is 7 Really the Magic Number for RBC Transfusion?
May 1, 2024
Over the past decade, there has been widespread adoption of restrictive red blood cell (RBC) transfusion guidelines.1,2 As a result, RBC transfusions have significantly decreased per...
Article
Can Pentoxifylline Improve Healing of Lower Extremity Ulcers?
May 1, 2024
Case The patient, Mr. D, has been experiencing swelling in his legs for several years, and seven months prior, he noticed that his skin had started to develop ulcers. He has class 3 obesity, type 2...
Article
Use of Amiodarone with Apixaban or Rivaroxaban Increases Risk for Bleeding-related Hospitalizations
March 1, 2024
Clinical question: Does the use of amiodarone in patients with atrial fibrillation increase the risk for bleeding-related hospitalizations when used with apixaban or rivaroxaban? Background:...
Article
ODS in Hospitalized Patients with Hyponatremia
September 1, 2023
Dr. Mohoney Clinical question: Of the patients who are admitted with hyponatremia, how many develop osmotic demyelination syndrome (ODS)? Background: ODS is a rare but serious complication...