Article
Oral Antibiotics and a Combination Regimen of IV and Oral Antibiotics for Treatment of Acute Uncomplicated Appendicitis Yielded Similar Success Rates
September 1, 2022
Dr. Andleeb Clinical question: Are oral antibiotics effective and non-inferior to a combination of intravenous and oral antibiotics? Background: Evidence over the past 10 years suggests that...
Article
Low-dose Rivaroxaban at Discharge Prevented Some VTE Events at One Month for High-risk Patients Recovering from COVID-19
September 1, 2022
Dr. Thazhatuveetil-Kunhahamed Clinical Question: Is extended rivaroxaban prophylaxis (10 mg daily for 35 days) protective against arterial and venous thromboembolism (VTE) events in COVID-19...
Article
Alcohol Withdrawal: Looking Beyond Benzodiazepines
June 1, 2022
Case Mr. Smith is a 48-year-old man with alcohol use disorder (AUD) and compensated cirrhosis who presented to the emergency department with alcohol withdrawal. He had been consuming one pint of...
Prescriptions for health and happiness
May 2, 2022
In addition to all the fear and chaos it has wreaked, COVID-19 has changed the way we think about our health. Thanks to the psychological, and even the physical, impacts of protracted quarantines and...
Article
What Medications Prevent Delirium in Elderly Medical Inpatients?
May 2, 2022
Case A 79-year-old man with a history of ischemic stroke five months ago presents with fever and shortness of breath. He is admitted for hypoxia secondary to suspected aspiration pneumonia and...
Article
Statins should be continued in hospitalized patients with COVID-19
May 2, 2022
Clinical question: Does discontinuation of atorvastatin in those hospitalized with COVID-19 change the risk of mortality and ventilation? Dr. Clark Background: Statins are ubiquitous. Statins...
Article
Efficacy of remdesivir in high-risk non-hospitalized patients
April 1, 2022
Dr. Taghvaei Clinical question: Does the use of remdesivir therapy in symptomatic, non-hospitalized, COVID-19 patients reduce disease progression and hospitalization? Background: Remdesivir...
Article
Outpatient COVID-19 therapeutics reduce hospitalization and mortality
February 10, 2022
Matching the right patient to the right therapeutic at the right time In late 2021 and early 2022, the Food and Drug Administration (FDA) granted emergency use authorizations (EUAs) for the...
Article
Aspirin increases the risk of clinically significant gastrointestinal bleeding in older persons
February 3, 2022
Clinical question: Does aspirin impact the risk of clinically significant gastrointestinal (GI) bleeding compared with placebo in community-dwelling older persons (aged >/= 70 years)? Dr....
Article
Effect of vasopressin and methylprednisolone versus placebo on return of spontaneous circulation in patients with in-hospital cardiac arrest
January 7, 2022
Dr. Miller Clinical question: Does the administration of vasopressin and methylprednisolone during in-hospital cardiac arrest improve the likelihood of return of spontaneous circulation...