Article
Coding Corner: Talk the Talk, Bill the Bill: Navigating Advance Care Discussion Billing
January 1, 2025
A 75-year-old woman with a previous medical history of high blood pressure, diabetes mellitus, stage 4 chronic kidney disease, and lung cancer was admitted to the hospital with chest pain and...
Article
Starting the Year with Gratitude
January 1, 2025
Reflecting on the past year as we begin a new one, I am grateful. Don’t get me wrong—there has been so much to knock me down over the last several months: personal loss, the seemingly endless...
Article
Efficacy of AI models in Detecting Clinical Deterioration
January 1, 2025
Clinical question: Can an artificial intelligence (AI) enabled intervention model reduce the risk of clinical deterioration and subsequent care escalation in hospitalized patients? Background:...
Article
Metronidazole-Related Encephalopathy and Neuropathy Associated with IV Administration, Liver Cirrhosis, and CKD
January 1, 2025
Clinical question: What is the prevalence of metronidazole-related neurologic adverse events and what are the risk factors associated with these events? Background: A 2021 study reported neurologic...
Article
Comparison of Hospital Mortality and Readmission Rates by Physician and Patient Sex
January 1, 2025
Clinical question: Are hospital mortality and readmission rates associated with physician sex, and do these associations vary by patient sex? Background: Prior studies indicate that physician...
Article
Inhaled Amikacin in the First 72 Hours of Mechanical Ventilation Reduced the Incidence of VAP
January 1, 2025
Clinical question: Does inhaled amikacin reduce the incidence of ventilator-associated pneumonia (VAP) in critically ill patients? Background: VAP is a common and serious complication in patients on...
Article
90-Day Mortality Among Septic Patients Given Piperacillin-Tazobactam Versus Cefepime
January 1, 2025
Clinical question: In patients with undifferentiated sepsis without an indication for anaerobic coverage, is there increased mortality with the combined use of vancomycin/piperacillin-tazobactam...
Article
Hydrocortisone Plus Fludrocortisone for CAP-Related Septic Shock
January 1, 2025
Clinical question: Does hydrocortisone and fludrocortisone reduce all-cause mortality among patients with septic shock due to community-acquired pneumonia (CAP)? Background: A meta-analysis of 17...
Article
Empagliflozin After Acute Myocardial Infarction (EMPACT-MI)
January 1, 2025
Clinical question: Does starting empagliflozin for patients with acute myocardial infarction (AMI) and new onset systolic heart failure (HF) or congestive symptoms reduce the risk of first...
Article
Clinical Risk Score Predicts Arterial Thrombosis in Survivors of Intracranial Hemorrhage
January 1, 2025
Clinical question: Among survivors of hemorrhagic stroke, who is at high long-term risk of arterial thrombosis? Background: Patients who survive intracerebral hemorrhage (ICH) are at increased risk...