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Uncomplicated Skin Infections in Ambulatory Setting Commonly Involve Avoidable Antibiotic Exposure
October 27, 2014
Clinical question: What are the current prescribing practices for antibiotics used to treat skin and soft tissue infections in the outpatient setting? Background: Uncomplicated skin and soft tissue infections are among the most frequent indications for outpatient antibiotic use.
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Resident Handoff Bundle Reduces Medical Errors and Adverse Events, Improves Handoff Quality
October 27, 2014
Clinical question: In a pediatric inpatient setting, is the use of a handoff program associated with improved patient safety measures and handoff quality? Background: Sentinel events related to errors in communication are a significant patient safety dilemma and an impetus for ongoing efforts to
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Modified IV Acetylcysteine Infusion Reduces Adverse Effects
October 27, 2014
Clinical question: Does a shorter regimen of IV acetylcysteine reduce adverse effects compared to the standard regimen? Background: Acetaminophen poisoning is common, and recommended treatment is IV acetylcysteine; however, the standard regimen has many adverse effects, including vomiting and ana
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No Mortality Benefit with Treatment of Single Peripheral Pulmonary Emboli
October 27, 2014
Clinical question: Does treatment of single peripheral pulmonary emboli impact mortality and rates of post-discharge venous thromboembolism (VTE)? Background: With the increase in CT pulmonary angiography (CTPA) use the past decade, there has been an increased rate of detection of peripheral fill
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Healthcare-Associated Infections Continue to Impact the U.S. Healthcare System Financially
October 27, 2014
Clinical question: What is the estimated cost of healthcare-associated infections (HAI) to the U.S. healthcare system? Background: In spite of education efforts, HAIs occur frequently and contribute to high healthcare costs in the U.S. This study sought to estimate the costs of HAIs to the U.S.
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Short Course of Oral Antibiotics Effective for Acute Osteomyelitis and Septic Arthritis in Children
October 27, 2014
By Mark Shen, MD Reviewed by Pediatric Editor Mark Shen, MD, medical director of hospital medicine at Dell Children’s Medical Center, Austin, Texas. Clinical question: Is a short course (less than four weeks) of antibiotics effective for the treatment of acute osteomyelitis and septic arthritis?
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Once-Weekly Antibiotic Might Be Effective for Treatment of Acute Bacterial Skin Infections
October 15, 2014
Research suggests intravenous dalbavancin similarly efficacious to intravenous vancomycin
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Continuous Positive Airway Pressure Outperforms Noctural Oxygen for Blood Pressure Reduction
October 15, 2014
CPAP better at decreasing 24-hour mean arterial pressure in patients with obstructive sleep apnea, coronary artery disease, cardiac risk factors
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Lactate Clearance Portends Better Outcomes after Cardiac Arrest
October 13, 2014
Lower lactate levels, greater clearance associated with better survival, neurological outcomes
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Time to Meds Matters for Patients with Cardiac Arrest Due to Nonshockable Rhythms
October 13, 2014
Earlier administration of epinephrine associated with better survival outcomes