Article
Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF
May 1, 2024
Dr. Watson Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)? Background: Studies have shown an increased risk of...
Article
High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF
May 1, 2024
Dr. Watson Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery,...
Article
SGLT-2 inhibitors May Decrease Recurrent Gout Flares in Patients with Type 2 diabetes
May 1, 2024
Dr. Bernal Clinical question: Do SGLT-2 inhibitors decrease gout flares in patients with type 2 diabetes and a known history of gout? Background: Sodium–glucose cotransporter-2 inhibitors...
Article
Semaglutide in Patients with HFpEF and Obesity
May 1, 2024
Dr. Cepeda Mora Clinical question: Is semaglutide an effective heart failure treatment in patients with heart failure with preserved ejection fraction (HFpEF) and obesity? Background: HFpEF is...
Article
Frailty Assessment and Perioperative Adverse Cardiovascular Events After Noncardiac Surgery
May 1, 2024
Dr. Chandler Clinical question: Can a frailty assessment tool be used to identify patients at higher risk for major adverse cardiac events (MACE) prior to noncardiac surgery? Background: Studies...
Article
Piperacillin-tazobactam Doesn’t Increase Risk of AKI Compared to Cefepime
May 1, 2024
Dr. Rhodes Clinical question: Do piperacillin-tazobactam and cefepime have similar risks of acute kidney injury (AKI)? Background: Observational studies have shown an association between...
Article
Back Off the Baclofen: Increased Risk of Encephalopathy
May 1, 2024
Dr. Sata Clinical question: Compared to other muscle relaxants, does baclofen increase the risk of encephalopathy? Background: Baclofen is a GABAergic muscle relaxant that is useful for patients...
Article
Torsemide or Furosemide After Discharge in Patients Hospitalized with HF
April 1, 2024
Clinical question: Is there a mortality difference in patients discharged on torsemide versus furosemide after heart failure hospitalization? Background: Torsemide has been thought to be superior to...
Article
Semaglutide in Patients with HFpEF and Obesity
April 1, 2024
Clinical question: Does treatment with semaglutide lead to a reduction in symptoms and physical limitations and improve exercise function in patients with heart failure with preserved ejection...
Article
VTEs and Their Effects on Patients with AE-COPD
April 1, 2024
Clinical question: How common are venous thromboembolisms (VTEs) in patients presenting with acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) and what is the effect on prognosis,...