News
Fecal Microbiotia Transplantation in Treatment of Recurrent Clostridium difficile Infection
July 14, 2015
Clinical question: Does fecal microbiotia transplantation (FMT) effectively treat patients with recurrent Clostridium difficile infection (CDI)? Background: Patients with initial CDI have increased rates of recurrence (15%–30%), with variable success noted in treatment of recurrent disease.
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ProMISe Trial Adds Skepticism to Early Goal-Directed Therapy for Sepsis
July 6, 2015
Clinical question: Does EGDT for sepsis reduce mortality at 90 days compared with standard therapy? Background: EGDT is recommended in international guidelines for the resuscitation of patients presenting with early septic shock; however, adoption has been limited, and uncertainty about its effec
News
Effectiveness of Multicomponent Nonpharmacological Delirium Interventions
July 6, 2015
Research Review: Nonpharmacological Delirium Interventions
News
Childhood Bacteremia and Antibiotics Usage in the Emergency Department
July 6, 2015
How vaccination against pneumococcus has changed microbiology of pediatric bacteremia
News
Patient Complexities Associated With Antibiotic Ordering
July 6, 2015
Research Review: Patient Complexities and Antibiotic Ordering
News
Predictors of Community-Acquired Pneumonia as Medical Emergency
July 6, 2015
Research Review: Community-Acquired Pneumonia as Medical Emergency
News
Effectiveness of Multicomponent Nonpharmacological Delirium Interventions
July 6, 2015
Research Review: Nonpharmacological Delirium Interventions
News
ProMISe Trial Adds Skepticism to Early Goal-Directed Therapy for Sepsis
July 6, 2015
Clinical question: Does EGDT for sepsis reduce mortality at 90 days compared with standard therapy? Background: EGDT is recommended in international guidelines for the resuscitation of patients presenting with early septic shock; however, adoption has been limited, and uncertainty about its effec
News
Predictors of Sepsis, Septic Shock in Emergency Department Patients
July 6, 2015
Clinical question: Among patients presenting to the ED with sepsis, who will progress to septic shock within 48 hours of arrival? Background: This study describes patient characteristics present within four hours of ED arrival associated with developing septic shock between four and 48 hours afte
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Individualized Patient Care Plans Impact Utilization, Costs
July 6, 2015
Clinical question: Does developing individualized care plans in the inpatient setting reduce unnecessary ED visits, hospital readmissions, and hospital costs for frequent users of hospital services? Background: High utilizers of healthcare services are recognized as medically and psychosocially c