News
Oral Steroids Not Inferior to Intravenous Steroids in Multiple Sclerosis Relapses
November 4, 2015
Clinical question: Is there any difference between oral and intravenous methylprednisolone for multiple sclerosis relapses? Background: When relapses of multiple sclerosis occur, studies have shown that intravenous steroids are the treatment of choice.
News
Clinical Care Pathway for Cellulitis Can Help Reduce Antibiotic Use, Cost
November 4, 2015
Clinical question: How would an evidence-based clinical pathway for cellulitis affect process metrics, patient outcomes, and clinical cost? Background: Cellulitis is a common hospital problem, but its evaluation and treatment vary widely.
News
Can Low-Risk Patients with VTE Be Discharged from ED on Rivaroxabon?
November 4, 2015
Clinical question: Can a low-risk patient newly diagnosed with VTE in the ED be immediately discharged home on a direct factor Xa inhibitor? Background: Studies have shown that rivaroxaban incurs a risk of 2.1% in VTE recurrence and of 9.4% in clinically relevant major and non-major bleeding (in
News
Coronary CT Angiography, Perfusion Imaging Effective for Evaluating Patients With Chest Pain
November 4, 2015
Clinical question: When evaluating the intermediate-risk patient with chest pain, should coronary computed tomography angiography (CCTA) be used instead of myocardial perfusion imaging (MPI)? Background: CCTA has been shown in prior randomized controlled trials to save time and money compared to
News
ED Lung Ultrasound Useful for Differentiating Cardiogenic from Noncardiogenic Dyspnea
November 4, 2015
Clinical question: Is lung ultrasound a useful tool for helping to diagnose acute decompensated heart failure (ADHF)? Background: Lung ultrasound is an emerging bedside tool that has been promoted to help evaluate lung water content to help clinicians differentiate ADHF from other causes of dyspn
News
Chemotherapy Does Not Improve Quality of Life with End-Stage Cancer
November 3, 2015
Clinical question: Does palliative chemotherapy improve quality of life (QOL) in patients with end-stage cancer, regardless of performance status? Background: There is continued debate about the benefit of palliative chemotherapy at the end of life.
News
Post-Operative Transfusions after Noncardiac Surgery Associated with Increased Adverse Outcomes
October 29, 2015
Clinical question: Do transfusions affect post-operative outcomes after noncardiac surgery? Background: Studies have demonstrated that a restrictive transfusion strategy is probably superior to a liberal transfusion strategy in many clinical settings.
News
Easing the Grieving Process for Families of Patients Dying in the ICU
October 29, 2015
Clinical question: Can we dignify death in the ICU and ease the grieving process by soliciting wishes from patients, families, and care team members? Background: The death of the critically ill patient in the ICU can be dehumanizing and overwhelming for the patient’s family and friends, leading t
![1]()
News
Pediatric Trigger Tool Helps Identify Inpatient Pediatric Harm
October 29, 2015
Clinical question: Can a trigger tool identify harms for hospitalized children? Background: An estimated 400,000 people die annually in the United States as a result of hospital-associated harm.
News
Left Atrial Appendage Closure Favorable Over Warfarin for Atrial Fibrillation
October 29, 2015
Clinical question: Is there a favorable risk-benefit ratio for left atrial appendage closure (LAAC) compared to warfarin for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvular atrial fibrillation? Background: LAAC with the WATCHMAN device was shown to be noninferior
