• 1
    News

    Isopropyl Alcohol Nasal Inhalation Effective Treatment for ED Nausea

    May 30, 2016

    Clinical question: Does inhaled isopropyl alcohol alleviate nausea as compared to inhaled saline solution among patients presenting to the ED with a chief complaint of nausea? Background: Nausea and vomiting account for 4.8 million ED visits each year; however, antiemetics have not shown superior

  • 1
    News

    Chronic Kidney Disease Risk with Proton Pump Inhibitors

    May 27, 2016

    Clinical question: What is the association between proton pump inhibitor (PPI) use and incident chronic kidney disease (CKD)? Background: Medication use may play a potential role in the increasing prevalence of CKD.

  • 1
    News

    Risk Factors for Pseudomonas, MRSA in Healthcare-Associated Pneumonia

    May 27, 2016

    Clinical question: What risk factors could predict the likelihood of Pseudomonas and methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized with healthcare-associated pneumonia (HCAP)? Background: Patients identified with HCAP have an increased risk for multi-drug-resistant p

  • 1
    News

    Updated CHEST Guidelines for Antithrombotic Therapy of VTE

    May 23, 2016

    Clinical question: What are the current recommendations for antithrombotic therapy in various venous thromboembolism (VTE) scenarios? Background: VTE is commonly encountered with a multitude of therapeutic options.

  • 1
    News

    Tamsulosin Can Be Used as Expulsive Therapy for Some Ureteric Stones

    May 23, 2016

    Clinical question: Is tamsulosin efficacious as an expulsive therapy for distal ureter stones ≤10 mm in diameter? Background: Ureteric calculi are a common reason for hospital admission, and use of medical expulsive therapy during observation periods for small caliber stones has gained much atten

  • 1
    News

    Prevalence, Characteristics of Physicians Prone to Malpractice Claims

    May 20, 2016

    Clinical question: Do claim-prone physicians account for a substantial share of all paid malpractice claims? Background: Many studies have compared physicians who have multiple malpractice claims against them with colleagues who have few or no claims against them and have identified systemic diff

  • 1
    News

    Association of Frailty on One-Year Postoperative Mortality Following Major Elective Non-Cardiac Surgery

    May 20, 2016

    Clinical question: What is the association of preoperative frailty on one-year postoperative mortality? Background: Frailty is an aggregate expression of susceptibility to poor outcomes owing to age and disease-related deficits that accumulate with multiple domains.

  • 1
    News

    Not All EDs Adopt Interventions to Improve Flow, Decrease Crowding

    May 6, 2016

    Clinical question: What is the relationship between crowding in the ED and the number of interventions adopted by the ED to address this? Background: ED crowding results in long waits, prolonged lengths of stay, and delays in providing treatments, which can result in adverse events.

  • 1
    News

    Close INR Monitoring Might Prevent Adverse Events

    May 6, 2016

    Clinical question: What is the appropriate frequency of INR monitoring in the hospital and its relationship to the risk of over-anticoagulation and warfarin-related adverse events? Background: Warfarin use is a common cause of adverse drug events in hospitalized patients due to narrow therapeutic

  • News

    Establishing a Role for Polysomnography in Hospitalized Children

    May 2, 2016

    Clinical question: What is the role for inpatient polysomnograms for children with medical complexity? [caption id="attachment_13645" align="alignright" width="150"] Dr. Stubblefield[/caption] Background: Sleep-disordered breathing is more common in certain pediatric populations.