Article
Higher Rates of Major Hemorrhage with Rivaroxaban and Warfarin
December 2, 2024
Clinical question: How effective and safe are apixaban versus rivaroxaban versus warfarin in patients with cirrhosis and nonvalvular atrial fibrillation (AF)? Background: Apixaban, rivaroxaban, and...
Article
Detectable MNPs in Carotid Artery Plaques Are Associated with a Higher Risk of Myocardial Infarction, Stroke, or Death
December 2, 2024
Clinical question: Do patients with carotid artery plaque containing detectable microplastics and nanoplastics (MNPs) have a higher risk of myocardial infarction, stroke, or death? Background:...
Article
Improving HF Outcomes in Obesity and Type 2 Diabetes: The Role of Semaglutide
December 2, 2024
Clinical question: Does semaglutide improve heart failure (HF) symptoms in patients with obesity-related HF and type 2 diabetes? Background: Obesity-related HF and type 2 diabetes are prevalent...
Article
Acute Cardiac Events are Common Among Adults 50 Years or Older Hospitalized with RSV and Associated with Severe Disease
December 2, 2024
Clinical question: How common are acute cardiac events among hospitalized older adults (50 years or older) with respiratory syncytial virus (RSV) infection and what are the associated risk...
Gastrointestinal Risks Associated with GLP-1 Receptor Agonists in Patients with Obesity
December 2, 2024
Clinical question: What is the risk of gastrointestinal adverse events associated with glucagon-like peptide-1 (GLP-1) receptor agonists used for weight loss compared to...
Article
Recurrence of Thromboses After Distal DVT
December 2, 2024
Clinical question: What is the incidence of recurrence of venous thrombosis after a distal deep vein thrombosis (DVT)? Background: Distal DVTs are frequently found but debate remains around whether...
Article
Summary of Advantages of GLP-1 Analogs in PCOS Patients
December 2, 2024
Clinical question: What is the role of glucagon-like peptide-1 (GLP-1) analogs in polycystic ovary syndrome (PCOS)? Background: GLP-1 analogs have been shown to improve outcomes in a variety of...
Article
Gabapentinoids and Risk for Severe Exacerbation in COPD
December 2, 2024
Clinical question: Is gabapentinoid use associated with severe exacerbation in patients with chronic obstructive pulmonary disease (COPD)? Background: The U.S. Food and Drug Administration issued a...
Article
Initiation of Medications for AUD Prior to Discharge Leads to Lower Rates of Return to Hospital
December 2, 2024
linical question: How does the initiation of medications for alcohol use disorder (AUD) at discharge affect 30-day post-discharge outcomes? Background: AUD is highly prevalent (affecting...
Article
A Stepwise Approach to Inpatient Management of Hypertension
December 2, 2024
Clinical question: How should clinicians approach the management of asymptomatic hypertension in inpatients? Background: There are heterogeneous practices to manage asymptomatic blood pressure (BP)...