Article
Questions Remain About Nirsevimab’s Impact
November 16, 2023
The new monoclonal antibody nirsevimab may radically change incidence and outcomes for respiratory syncytial virus (RSV) infections in young pediatric patients, especially when combined with the...
Article
Simple Ways to Start FBT for Eating Disorders in the Hospital
November 1, 2023
Dr. Musaitif Presenters: Christiane Lenzen, MD, and Tamara Maginot, PhD Eating disorders are illnesses that affect children, adolescents, and adults and are associated with significant morbidity...
Article
Direct Oral Challenge is Non-inferior to Skin Testing in Low-risk Penicillin Allergy Patients
October 2, 2023
Clinical question: Is there an alternative to penicillin skin testing for low-risk penicillin allergies? Dr. Miller Background: While approximately 10% of the population report...
Article
Deprescribing Medications Among Older Adults from the End of Hospitalization Through Post-acute Care
October 2, 2023
Clinical question: Can inpatient deprescribing interventions upon post-acute care facility discharge reduce the total medication burden? Dr. Kaur Background: Polypharmacy remains a common...
Article
Weighing Benefits and Risks of Indefinite Anticoagulation in First Unprovoked VTE
October 2, 2023
Clinical question: Is indefinite anticoagulation beneficial for patients with a first unprovoked venous thromboembolism (VTE) after initial treatment? Dr. Sheikh Background: VTE is a chronic,...
Article
Pitavastatin and Cardiovascular Disease Prevention in HIV Patients
October 2, 2023
Clinical question: Does pitavastatin reduce the risk of cardiovascular disease in human immunodeficiency virus (HIV)-infected individuals? Dr. Sheikh Background: Individuals with HIV infection...
Article
No Difference Between Liberal Versus Strict Perioperative BP Management in Non-cardiac Surgery
October 2, 2023
Clinical question: In patients on antihypertensive medications (AHMs) such as angiotensin-converting-enzyme inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) undergoing inpatient...
Article
DAPT Non-inferior to Alteplase for Minor AIS
October 2, 2023
Clinical question: Is dual antiplatelet therapy (DAPT) non-inferior to intravenous (IV) thrombolysis in patients with minor non-disabling acute ischemic strokes (AIS)? Dr....
Article
Intensive BP Control with PO or IV Harmful in Hospitalized Older Adults
October 2, 2023
Clinical question: How do clinical outcomes compare between patients with asymptomatic hypertension treated intensively versus not while hospitalized? Dr. Richardson Background: While the...
Article
Delayed Antibiotics in Suspected Sepsis Increase Shock Risk and Mortality
October 2, 2023
Clinical question: Does the time to first antibiotics affect the risk of progression to septic shock? Dr. Richardson Background: The Surviving Sepsis Campaign emphasized early infection...