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Caprini Risk Assessment Tool Can Distinguish High Risk of VTE in Critically Ill Surgical Patients
December 1, 2015
Clinical question: Is the Caprini Risk Assessment Model for VTE risk valid in critically ill surgical patients? Background: Critically ill surgical patients are at increased risk of developing VTE. Chemoprophylaxis decreases VTE risk, but benefits must be balanced against bleeding risk.
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Adherence to Restrictive Red Blood Cell Transfusion Guidelines Improved with Peer Feedback
December 1, 2015
Clinical question: Can a multifaceted approach involving clinician education, peer email feedback, and monthly audit data improve adherence to restrictive red blood cell (RBC) transfusion guidelines? Background: Randomized controlled trials and professional society guidelines support adoption of
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Corticosteroids Improve Outcomes in Community- Acquired Pneumonia
December 1, 2015
Clinical question: Are adjunctive corticosteroids beneficial for patients hospitalized with community-acquired pneumonia (CAP)? Background: Numerous studies have tried to determine whether or not adjunctive corticosteroids for CAP treatment in hospitalized patients improve outcomes.
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Standard Triple Therapy for H. Pylori Lowest Ranked among 14 Treatment Regimens
December 1, 2015
Clinical question: How do current Helicobacter pylori treatments compare in efficacy and tolerance? Background: Efficacy of standard “triple therapy” for H.
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Social Isolation, Polypharmacy Predict Medication Noncompliance Post-Discharge in Cardiac Patients
December 1, 2015
Clinical question: What are predictors of primary medication nonadherence after discharge? Background: Primary nonadherence occurs when a patient receives a prescription at hospital discharge but does not fill it.
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Inpatient Navigators Reduce Length of Stay without Increasing Readmissions
December 1, 2015
Clinical question: Does a patient navigator (PN) who facilitates communication between patients and providers impact hospital length of stay (LOS) and readmissions? Background: Increasing complexity of hospitalization challenges the safety of care transitions.
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Dexamethasone Potential Therapy for Asthma Exacerbations in Pediatric Inpatients
December 1, 2015
Clinical question: In children hospitalized in a non-ICU setting with asthma exacerbation, how effective is dexamethasone compared to prednisone/prednisolone? Background: Asthma is the second most common reason for hospital admission in childhood.1 National guidelines recommend treatment with sys
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What Are the Strategies for Secondary Stroke Prevention after Transient Ischemic Attack?
December 1, 2015
Case Mr. G is an 80-year-old man with a pacemaker, peripheral artery disease, atrial fibrillation (AF) on warfarin, and tachy-brady syndrome. He presented after experiencing episodes in which he was unable to speak and had weakness on his right side.
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Elderly Patients with Pneumonia Benefit from ICU Care
November 18, 2015
NEW YORK - Elderly patients with pneumonia whose need for intensive care unit (ICU) admission is uncertain actually fare better in the ICU than on the general medical ward, a new study suggests. "Although our results should be confirmed with a randomized trial, clinicians should be aware that man
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Younger Type 2 Diabetics Face Greater Mortality Risks
November 11, 2015
NEW YORK - People with type 2 diabetes are 15 percent more likely to die from any cause and 14 percent more likely to die from a cardiovascular cause than non-diabetics at any given time, according to data from several Swedish registries. The rates are significantly lower than previous estimates.