Drug doses for heart failure could possibly be halved for women

SOURCE: Santema BT et al. Lancet. 2019 Aug 22. doi: 10.1016/S0140-6736(19)31792-1.

Real-world Application of Oral Therapy for Infective Endocarditis
September 12, 2019
Dr. Chadwick Clinical question: Does oral transitional antibiotic therapy have similar outcomes to intravenous (IV)-only antibiotic treatment for infective endocarditis (IE)? Background: There...
Acetaminophen Rises Systolic Blood Pressure in Those with Hypertension
September 12, 2019
Clinical question: Does regular intake of acetaminophen cause an increase in blood pressure? Background: Acetaminophen is one of the most commonly used analgesics in the world. Because of its...

Effect of vasopressin and methylprednisolone versus placebo on return of spontaneous circulation in patients with in-hospital cardiac arrest
September 12, 2019
Dr. Miller Clinical question: Does the administration of vasopressin and methylprednisolone during in-hospital cardiac arrest improve the likelihood of return of spontaneous circulation...
Dapagliflozin trial in CKD halted because of high efficacy
September 12, 2019
An independent data monitoring committee recommended stopping the trial.

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