The study’s primary outcome was surgical site infection, which was assessed regularly during the hospital stay, at discharge, and by clinic visit or telephone call 30 days after discharge. The secondary outcomes were deep space surgical site infections and infections caused specifically by ESBL-B. ESBL-B was significantly associated with both surgical site infection (OR 2.25) and deep space infection (OR 2.25).
A multivariate analysis controlled for age, cardiovascular disease, indication for surgery, and whether the procedure included a rectal resection, retention of drain at the surgical site, or stoma. The model also controlled for National Nosocomial Infection Surveillance score, a three-point scale that estimates surgical infection risk. Among this cohort, 48% were at low risk, 43% at moderate risk, and 10% at high risk.
Dr. Carmeli made no financial disclosures.
SOURCE: Carmeli et al, ECCMID 2018, Oral Abstract O1133.
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