Regina Makdissi, MD
News
ProMISe Trial Adds Skepticism to Early Goal-Directed Therapy for Sepsis
July 6, 2015
Clinical question: Does EGDT for sepsis reduce mortality at 90 days compared with standard therapy? Background: EGDT is recommended in international guidelines for the resuscitation of patients presenting with early septic shock; however, adoption has been limited, and uncertainty about its effec
News
Effectiveness of Multicomponent Nonpharmacological Delirium Interventions
July 6, 2015
Research Review: Nonpharmacological Delirium Interventions
News
Patient Complexities Associated With Antibiotic Ordering
July 6, 2015
Research Review: Patient Complexities and Antibiotic Ordering
News
Predictors of Community-Acquired Pneumonia as Medical Emergency
July 6, 2015
Research Review: Community-Acquired Pneumonia as Medical Emergency
News
Effectiveness of Multicomponent Nonpharmacological Delirium Interventions
July 6, 2015
Research Review: Nonpharmacological Delirium Interventions
News
ProMISe Trial Adds Skepticism to Early Goal-Directed Therapy for Sepsis
July 6, 2015
Clinical question: Does EGDT for sepsis reduce mortality at 90 days compared with standard therapy? Background: EGDT is recommended in international guidelines for the resuscitation of patients presenting with early septic shock; however, adoption has been limited, and uncertainty about its effec
News
Predictors of Sepsis, Septic Shock in Emergency Department Patients
July 6, 2015
Clinical question: Among patients presenting to the ED with sepsis, who will progress to septic shock within 48 hours of arrival? Background: This study describes patient characteristics present within four hours of ED arrival associated with developing septic shock between four and 48 hours afte
News
Individualized Patient Care Plans Impact Utilization, Costs
July 6, 2015
Clinical question: Does developing individualized care plans in the inpatient setting reduce unnecessary ED visits, hospital readmissions, and hospital costs for frequent users of hospital services? Background: High utilizers of healthcare services are recognized as medically and psychosocially c
News
Revised Guideline for Adult Bacterial Meningitis Improves Treatment, Outcome
July 6, 2015
Clinical question: Did revision of guidelines recommending computerized tomography (CT) scan before lumbar puncture (LP) reduce delayed treatment of acute bacterial meningitis (ABM)? Background: Guidelines were introduced in Sweden in 2004 identifying patients at risk for LP-induced brain herniat
News
Multifaceted Intervention to Decrease Frequency of Common Labs
July 6, 2015
Clinical question: Can a multifaceted intervention decrease the frequency of unnecessary labs? Background: Implementation of a multifaceted QI intervention within a large, community-based hospitalist group to decrease ordering of common labs. Study design: QI project. Setting: Large, commun