Matthew Hill, MD, FHM
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Short-Course Antimicrobial Therapy Outcomes for Intra-Abdominal Infection
September 22, 2015
Clinical question: Does a short, fixed duration of antibiotic therapy for complicated intra-abdominal infections lead to equivalent outcomes and less antibiotic exposure than the traditional approach? Background: Published guidelines recommend appropriate antimicrobial agents for intra-abdominal
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Post-Procedural Bridging Therapy for Secondary Prevention of VTE Increases Rate of Bleeding
September 9, 2015
Research Review: Post-Procedural Bridging Therapy and VTE Prevention
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Short-Course Antimicrobial Therapy Outcomes for Intraabdominal Infection
September 9, 2015
Research Review: Short-Course Antimicrobial Therapy for Intraabdominal Infection
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Effects of Peri-Operative Beta-Blockade in Noncardiac Surgery Vary Based on Cardiac Risk Factors
September 9, 2015
Research Review: Peri-Operative Beta-Blockade in Noncardiac Surgery
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Risk for In-Hospital Adverse Cardiac Events Low for Some Patients with Chest Pain
September 9, 2015
Clinical question: Do stable, low-risk patients hospitalized for chest pain after negative ED evaluation experience adverse cardiac events in the hospital? Background: Chest pain results in more than seven million ED visits annually, with a cost of over $11 billion to hospitalize these patients f
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New Strategy in Patients with Suspected Heparin-Induced Thrombocytopenia Improves Diagnostic Accuracy
September 9, 2015
Clinical question: Can a diagnostic strategy that utilizes a clinical prediction rule combined with an immunoassay appropriately guide management for patients with suspected heparin-induced thrombocytopenia (HIT)? Background: The appropriate and timely diagnosis of HIT can decrease the risks of t
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Vasoactive Medications Safe in ICU via Peripheral Intravenous Access
September 9, 2015
Clinical question: Can vasoactive medications be safely given in the ICU via peripheral intravenous (PIV) access instead of central venous access? Background: Vasoactive medications are given to a variety of patients in shock to maintain hemodynamic function.
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Cost, Frequency of Emergency Department Revisits Evaluated
September 9, 2015
Clinical question: What is the cost and frequency of ED revisits within three days and 30 days? Background: ED revisits lead to a financial and resource utilization burden on the medical system.
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Early, Late Hospital Readmission Factors Differ
September 9, 2015
Clinical question: What are the differences between factors associated with early (zero to seven days after discharge) and late (eight to 30 days after discharge) readmission? Background: Thirty-day readmission rates are a quality metric; however, recent evidence challenges the notion that readmi
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Patient Adherence to Pharmacological Thromboprophylaxis Improves with Interventions
September 9, 2015
Clinical question: How can patient adherence to pharmacological thromboprophylaxis be improved? Background: Prior studies suggest that the hospital-wide prevalence of nonadministration of VTE thromboprophylaxis orders ranges from 5% to 13%, with patient refusal listed as the most common reason fo