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News
Disinfection Caps Reduce CLABSI, BCC in Hematology-Oncology Patients
May 30, 2016
Clinical question: Does the use of disinfection caps on catheter hubs on central venous catheters (CVCs) reduce central-line-associated bloodstream infection (CLABSI) and blood culture contamination (BCC) in hematology-oncology patients? Background: CVCs have facilitated the administration of che
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News
Isopropyl Alcohol Nasal Inhalation Effective Treatment for ED Nausea
May 30, 2016
Clinical question: Does inhaled isopropyl alcohol alleviate nausea as compared to inhaled saline solution among patients presenting to the ED with a chief complaint of nausea? Background: Nausea and vomiting account for 4.8 million ED visits each year; however, antiemetics have not shown superior
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News
Chronic Kidney Disease Risk with Proton Pump Inhibitors
May 27, 2016
Clinical question: What is the association between proton pump inhibitor (PPI) use and incident chronic kidney disease (CKD)? Background: Medication use may play a potential role in the increasing prevalence of CKD.
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Risk Factors for Pseudomonas, MRSA in Healthcare-Associated Pneumonia
May 27, 2016
Clinical question: What risk factors could predict the likelihood of Pseudomonas and methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized with healthcare-associated pneumonia (HCAP)? Background: Patients identified with HCAP have an increased risk for multi-drug-resistant p
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News
Updated CHEST Guidelines for Antithrombotic Therapy of VTE
May 23, 2016
Clinical question: What are the current recommendations for antithrombotic therapy in various venous thromboembolism (VTE) scenarios? Background: VTE is commonly encountered with a multitude of therapeutic options.
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News
Tamsulosin Can Be Used as Expulsive Therapy for Some Ureteric Stones
May 23, 2016
Clinical question: Is tamsulosin efficacious as an expulsive therapy for distal ureter stones ≤10 mm in diameter? Background: Ureteric calculi are a common reason for hospital admission, and use of medical expulsive therapy during observation periods for small caliber stones has gained much atten
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Prevalence, Characteristics of Physicians Prone to Malpractice Claims
May 20, 2016
Clinical question: Do claim-prone physicians account for a substantial share of all paid malpractice claims? Background: Many studies have compared physicians who have multiple malpractice claims against them with colleagues who have few or no claims against them and have identified systemic diff
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News
Association of Frailty on One-Year Postoperative Mortality Following Major Elective Non-Cardiac Surgery
May 20, 2016
Clinical question: What is the association of preoperative frailty on one-year postoperative mortality? Background: Frailty is an aggregate expression of susceptibility to poor outcomes owing to age and disease-related deficits that accumulate with multiple domains.
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News
Postoperative Clostridium Difficile Infection Associated with Number of Antibiotics, Surgical Procedure Complexity
April 8, 2016
Clinical question: What are the factors that increase risk of Clostridium difficile infection (CDI) in postoperative patients? Background: CDI has become an important infectious etiology for morbidity, lengthy and costly hospital admissions, and mortality.
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News
Most Postoperative Readmissions Due to Patient Factors
April 8, 2016
Clinical question: What is the etiology of 30-day readmissions in postoperative patients? Background: As the focus of healthcare changes to a quality-focused model, readmissions impact physicians, reimbursements, and patients.
